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Antonio Mancini was an Italian painter. Mancini was born in Rome and showed precocious ability as an artist. At the age of twelve he was admitted to the Institute of Fine Arts in Naples, where he studied under Domenico Morelli (1823–1901), a painter of historical scenes who favored dramatic chiaroscuro and vigorous brushwork, and Filippo Palizzi (1818–1899), a landscape painter. Mancini developed quickly under their guidance, and in 1872 he exhibited two paintings at the Paris Salon.

His painting,The Poor Schoolboy, exhibited in the Salon of 1876, is now in the Musee d'Orsay. Its realist subject matter and dark palette is typical of his early work.